Trajectory

Absorptive

All cells

All samples trajectory

## [1] "Anno1"

## [1] "Anno2"

anno2 and State
1 2 3 4 5 6 7
ACE2+ Proximal EC 7 101 136 1036 0 186 47
BEST4 EC 152 4 0 15 183 106 27
Distal EC progenitor 511 0 0 0 10 0 0
Distal-EC2 1 0 0 0 3 31 0
Early Distal-EC 380 0 0 2 37 2 0
Early Proximal-EC 1358 31 0 99 189 24 764
Int Distal-EC 34 1 0 7 40 33 2
Int Proximal-EC 248 945 722 2052 443 834 993
Mature Distal-EC 4 1 1 7 6 43 4
Mature Proximal-EC 111 471 1182 5530 288 4101 242
Microfold 12 9 7 368 21 609 8
MT-low Mature Proximal-EC 6 9 86 2426 63 8920 3
Proximal EC progenitor 1460 0 0 0 18 0 0
Stem 755 0 0 0 9 0 0
TA 1356 0 0 1 60 6 1 
## [1] "Anno1"

## [1] "Anno2"

## [1] "Inf status"

## [1] "Stem"

Healthy

Healthy trajectory

## [1] "Anno1"

## [1] "Anno2"

anno2 and State
1 2 3 4 5
ACE2+ Proximal EC 508 495 14 1 55
BEST4 EC 27 11 2 54 212
Distal EC progenitor 0 0 0 0 22
Early Distal-EC 0 0 0 0 27
Early Proximal-EC 17 226 6 17 847
Int Proximal-EC 815 1675 66 112 365
Mature Distal-EC 0 1 0 0 1
Mature Proximal-EC 3776 2300 45 42 93
Microfold 211 52 1 5 0
MT-low Mature Proximal-EC 6101 259 4 3 9
Proximal EC progenitor 0 0 0 0 789
Stem 0 0 0 0 348
TA 1 0 0 2 383 
## [1] "Anno1"

## [1] "Anno2"

## [1] "Stem"

## [1] "EC markers"

non-Inf

non-Inf trajectory

## [1] "Anno1"

## [1] "Anno2"

anno2 and State
1 2 3
ACE2+ Proximal EC 215 278 62
BEST4 EC 38 2 173
Distal EC progenitor 0 0 426
Distal-EC2 36 0 5
Early Distal-EC 1 0 369
Early Proximal-EC 15 207 857
Int Distal-EC 24 2 123
Int Proximal-EC 502 1695 996
Mature Distal-EC 52 3 20
Mature Proximal-EC 2443 2583 934
Microfold 677 115 135
MT-low Mature Proximal-EC 4343 664 114
Proximal EC progenitor 0 0 628
Stem 0 0 340
TA 4 0 897 
## [1] "Anno1"

## [1] "Anno2"

## [1] "Stem"

## [1] "EC markers"

Inf

Inf trajectory

## [1] "Anno1"

## [1] "Anno2"

anno2 and State
1 2 3 4 5
ACE2+ Proximal EC 43 0 0 0 0
BEST4 EC 9 1 3 3 1
Distal EC progenitor 2 0 1 185 12
Early Distal-EC 2 0 8 113 25
Early Proximal-EC 46 44 357 110 16
Int Proximal-EC 197 429 53 0 0
Mature Distal-EC 2 0 4 1 0
Mature Proximal-EC 646 242 3 0 0
Microfold 93 1 3 0 0
MT-low Mature Proximal-EC 1103 10 1 0 0
Proximal EC progenitor 0 0 2 115 6
Stem 0 0 1 109 30
TA 0 0 3 397 27 
## [1] "Anno1"

## [1] "Anno2"

## [1] "Stem"

## [1] "EC markers"

Secretory

All cells

All samples trajectory

## [1] "Anno1"

## [1] "Anno2"

anno2 and State
1 2 3 4 5
AC-Goblet 64 181 334 5 7
Early AC-goblet 1 18 215 3 3
Early TI-Goblet 21 240 570 12 4
Stem 0 19 907 18 1
TA 3 45 1678 138 21
TI-Goblet 4425 425 38 2 156
TI-Goblet2 1 16 22 168 1148 
## [1] "Anno1"

## [1] "Anno2"

## [1] "Inf status"

## [1] "Goblet"

## [1] "Goblet cluster markers"

Other

All cells

All samples trajectory

## [1] "Anno1"

## [1] "Anno2"

anno2 and State
1 2 3 4 5
EEC 651 15 5 5 18
Paneth 566 5 2 1 23
Stem 11 9 0 11 914
TA 120 109 116 1504 36
Tuft 376 9 5 3 20 
## [1] "Anno1"

## [1] "Anno2"

## [1] "Inf status"

## [1] "Stem"